Bruch’s Membrane Opening Minimum Rim Width Measurement with SD-OCT: A Method to Correct for the Opening Size of Bruch’s Membrane

Figure 1

A schematic illustration of two different ONH sizes: (a) small and (b) large. The upper images depict fundus images with red main vessels and the optic nerves (the neuroretinal rim area is marked in yellow and the excavation is marked in white inside the ONH), while the lower images feature horizontal cross-sectional OCT images through the middle of the optic nerves (with a yellow RNFL). The neuroretinal rim areas, and therefore the total number of axons, are equal in both (a) and (b). However, the BMO-MRW (indicated by green arrows in the lower images) is reduced in image (b). The hypothesis is that the BMO-MRW is influenced by ONH size and requires correction for use in valid comparisons within a cohort.

(a)

(b)