Clinical Study

Two-Year Outcome of Aflibercept in Patients with Pigment Epithelial Detachment due to Neovascular Age-Related Macular Degeneration (nAMD) Refractory to Ranibizumab

Table 3

Qualitative analysis of SD-OCT at different time points.

Number of eyesMonth 0Month 4Month 6Month 12Month 24

SRF26 (59%)13 (29.5%)16 (37.2%)18 (47.3%)17 (44.7%)
IRF22 (50%)9 (20.4%)9 (20.9%)20 (52.6%)16 (42.1%)
No fluid0 (0%)18 (59%)23 (53.4%)10 (26.3%)13 (34.3%)
SHE18 (40.9%)2 (4.5%)1 (2.3%)5 (13.1%)5 (13.1%)
IS/OS disruptions19 (43.2%)17 (38.6%)16 (37.2%)17 (44.7%)30 (78.9%)

SRF: subretinal fluid; IRF: intraretinal fluid; SHE: subretinal hyperreflective exudation; IS/OS: inner segment/outer segment.