Simultaneous Fluorescein Angiography and Spectral Domain Optical Coherence Tomography Correlate Retinal Thickness Changes to Vascular Abnormalities in an In Vivo Mouse Model of Retinopathy of Prematurity
Spectral domain optical coherence tomography and corresponding thickness color map in P47 RA mouse. (a) Boundaries of the inner retina and outer retina. (b) Thickness color map for the SD-OCT generated from delineating the retinal boundaries. Line 1 was made at the superior boundary of inner limiting membrane (ILM). Line 2 was made at the lower edge of the IPL. Line 3 was made at the inferior boundary of the PRL. Lines 1 to 3: total retinal thickness is measured. Lines 1 to 2: inner retinal thickness is measured. Lines 2 to 3: outer retinal thickness is measured. Note: SD-OCT refers to spectral domain optical coherence tomography. Lines refer to linear segmentation lines.