Simultaneous Fluorescein Angiography and Spectral Domain Optical Coherence Tomography Correlate Retinal Thickness Changes to Vascular Abnormalities in an In Vivo Mouse Model of Retinopathy of Prematurity

Figure 2

Spectral domain optical coherence tomography and corresponding thickness color map in P47 RA mouse. (a) Boundaries of the inner retina and outer retina. (b) Thickness color map for the SD-OCT generated from delineating the retinal boundaries. Line 1 was made at the superior boundary of inner limiting membrane (ILM). Line 2 was made at the lower edge of the IPL. Line 3 was made at the inferior boundary of the PRL. Lines 1 to 3: total retinal thickness is measured. Lines 1 to 2: inner retinal thickness is measured. Lines 2 to 3: outer retinal thickness is measured. Note: SD-OCT refers to spectral domain optical coherence tomography. Lines refer to linear segmentation lines.

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