Retinal Vessel Density in Optical Coherence Tomography Angiography in Optic Atrophy after Nonarteritic Anterior Ischemic Optic Neuropathy

Table 2

Mean values and diagnostic accuracy (AUROC) of vessel density and RNFL and GCC thicknesses^b.

Diagnostic parameters	NAION eyes ()	Controls ()	value	95% CI of the difference	AUROC
wiVD, %	43.9 (6.4) [37.1~58.9]	53.6 (3.4) [48.2~59.5]	<0.001^a	−13.8~−5.6	0.970
cpVD, %	48.3 (7.7) [37.0~64.9]	61.6 (3.0) [55.6~68.1]	<0.001^a	−18.1~−8.4	0.992
pfVD, %	44.9 (4.9) [34.2~50.2]	44.1 (3.5) [38.5~49.7]	0.49	−3.0~4.4	0.409
Average RNFL thickness, μm	79.3 (27.8) [46.0~152.0]	98.3 (7.6) [87.0~112.0]	0.001^a	−35.5~−2.6	0.909
Average GCC thickness, μm	75.3 (10.3) [55.2~88.1]	102.5 (29.7) [88.8~219.9]	<0.001^a	−44.8~−9.6	1.000

NAION: nonarteritic anterior ischemic optic neuropathy; CI: confidence interval; AUROC: area under the receiver operating characteristic; wiVD: whole en face image vessel density; cpVD: circumpapillary vessel density; pfVD: parafoveal vessel density; RNFL: retinal nerve fiber layer; GCC: ganglion cell complex.
^aStatistically significant.
^bUnless otherwise indicated, data are given as the mean (standard deviation) [range].