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Journal of Ophthalmology
Volume 2017, Article ID 9640756, 5 pages
Clinical Study

The Comparison of the Surgical Outcome for the Full-Thickness Macular Hole with/without Lamellar Hole-Associated Epiretinal Proliferation

1Department of Surgery-Related, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan
2Department of Ophthalmology, Kitaharima General Medical Center, 926-250 Ichiba-cho, Ono 675-1392, Japan
3Department of Ophthalmology, Kakogawa Nishi Municipal Hospital, 384-1 HIratsu, Yoneda-cho, Kakogawa 675-0054, Japan
4Department of Ophthalmology, Mitsubishi Kobe Hospital, 6-1-34 Wadamiya Street, Hyogo-ku, Kobe 652-0863, Japan
5Department of Ophthalmology, Kobe Kaisei Hospital, 3-11-15 Shinoharakitamachi, Nada-ku, Kobe 657-0068, Japan

Correspondence should be addressed to Hisanori Imai;

Received 10 August 2017; Revised 10 November 2017; Accepted 23 November 2017; Published 13 December 2017

Academic Editor: Hyeong Gon Yu

Copyright © 2017 Yuri Ubukata et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Aims. To compare the surgical outcome of pars plana vitrectomy (PPV) for full-thickness macular hole (FTMH) with and without lamellar hole-associated epiretinal proliferation (LHEP). Methods. This retrospective study included 158 eyes of 158 patients with FTMH treated with PPV. The following variables were analyzed: sex, age, preoperative best corrected visual acuity (pre-BCVA), BCVA 6 months after the surgery (6M-BCVA), the axial length of eye, the minimum diameter of FTMH, the diameter of basal side of FTMH, postoperative continuity of subfoveal ellipsoid zone (EZ) and external limiting membrane (ELM), and the preoperative presence of LHEP. Results. Twenty-eight eyes had FTMH with LHEP and 130 without LHEP. The mean ± SD age (years) was 72.6 ± 7.9 and 68.6 ± 8.7, respectively (). 6M-BCVA was 0.38 ± 0.30 and 0.26 ± 0.25, respectively (). The diameter of basal side of FTMH (μm) was 901.5 ± 404.9 and 658.9 ± 288.1, respectively (). EZ was disrupted in 24 eyes and 63 eyes, respectively (). ELM was disrupted in 15 eyes and 23 eyes, respectively (). The FTMH diameters and the presence of LHEP were inversely correlated with the continuity of EZ and ELM. Conclusion. The preoperative appearance of LHEP could be one of the prognostic factor for the treatment of FTMH.