Review Article
The Association between Adiposity and the Risk of Glaucoma: A Meta-Analysis
Table 3
Results of subgroup analysis between adiposity and glaucoma with pooled RR.
| | Subgroups | Number of studies | RR (95% CI) | I2, % | Heterogeneity value |
| | Study design | Cohort | 5 | 1.00 (0.84–1.20) | 84.10% | <0.001 | | Cross-sectional | 9 | 1.22 (0.89–1.66) | 88.60% | <0.001 | | Gender | Male | 6 | 1.11 (0.77–1.60) | 91.80% | <0.001 | | Female | 8 | 1.31 (1.05–1.64) | 80.30% | <0.001 | | Smoking | Yes | 5 | 1.18 (0.93–1.48) | 68.20% | 0.014 | | No | 10 | 1.13 (0.90–1.41) | 91.20% | <0.001 | | Alcohol intake | Yes | 4 | 1.26 (1.04–1.54) | 57.60% | 0.069 | | No | 11 | 1.09 (0.87–1.35) | 90.50% | <0.001 | | Physical activity | Yes | 4 | 1.26 (1.04–1.54) | 57.60% | 0.069 | | No | 11 | 1.09 (0.87–1.35) | 90.50% | <0.001 | | Hypertension | Yes | 7 | 1.28 (0.98–1.69) | 93.20% | <0.001 | | No | 8 | 1.02 (0.80–1.29) | 77.50% | <0.001 | | Diabetes mellitus | Yes | 5 | 1.35 (0.96–1.91) | 94.30% | <0.001 | | No | 10 | 1.03 (0.83–1.29) | 82.20% | <0.001 | | Other metabolic syndrome components | Yes | 4 | 0.92 (0.72–1.18) | 82.60% | 0.001 | | No | 11 | 1.23 (0.98–1.56) | 86.30% | <0.001 | | CCT | Yes | 2 | 0.92 (0.48–1.75) | 80.10% | 0.025 | | No | 13 | 1.17 (0.97–1.41) | 89.40% | <0.001 |
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RR: relative risk; CI: confidence interval; CCT: central corneal thickness.
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