Research Article

Tear Ferning Test and Pathological Effects on Ocular Surface before and after Topical Cyclosporine in Vernal Keratoconjunctivitis Patients

Table 1

Clinical and demographic characteristics of 47 VKC patients.

Age range3–16 years
Age (average ± SD)8.8 ± 4.7 years
VKC onset (average ± SD)2.7 ± 1.3 years
Sex: male and female38 (79.85%) 9 (20.15%)
Forms of VKCTarsal: 30 (63.83%)
Limbal: 12 (25.53%)
Mixed: 3 (6.38%)
Corneal: 2 (4.26%)
Total score of signs12.5 ± 2.0 SD
Total score of symptoms8.1 ± 2.1 SD
TFT score (average ± SD)2.43 ± 0.80
Lacrimal MUC5AC (pg/ml)4,103.33 ± 286.35 SD
Density goblet (cells/field)30.0 ± 20.0 SD

Score of signs (TSS)Average ± SD
Hyperemia/chemosis conjunctival2.5 ± 0.5
Mucous and serious secretions2.3 ± 0.7
Tarsal papillae < 3 mm2.3 ± 0.5
Tarsal papillae > 3 mm2.2 ± 0.4
Horner–Trantas nodules2.5 ± 0.2
Epithelial keratitis0.5 ± 0.02

Score of symptoms (TSyS)Average ± SD
Itching and photophobia4.0 ± 0.7
Tearing2.1 ± 0.8
Foreign body sensation2.0 ± 0.6

VKC: vernal keratoconjunctivitis; SD: standard deviation; TFT: tear ferning test.