Table 2: Comparison of topical adverse effects of the four prostaglandins in primary open-angle glaucoma patients controlled by monotherapy.

Bimatoprost ()Latanoprost ()Travoprost ()Tafluprost () value

Adverse effect, n (%)
 Conjunctival hyperemia6 (75.0)5 (71.4)4 (50.0)9 (100.0)0.13
 Superficial keratitis4 (50.0)4 (57.1)3 (3.8)3 (33.3)0.76
 Follicular conjunctivitis2 (25.0)4 (57.1)3 (3.8)5 (55.5)0.51
 Iris hyperpigmentation0 (0)2 (28.6)0 (0)0 (0)0.05
 Eyelash growth1 (12.5)4 (57.1)2 (25.0)0 (0)0.05
 Herpetic reactivation0 (0)1 (14.3)0 (0)0 (0)0.30