|
| Study | Risk factors discussed in the researches | Sample size | Outcome |
| Significant factors | Not significant factors |
|
| Lass et al. [3] | — | Donor status (history of diabetes) | 1090 | Graft failure and ECD at 10 years |
| Sugar et al. [7] | Recipient factors (age, indication, glaucoma, smoking) | Recipient factors (race, sex, diabetes) | 1090 | Graft failure at 10 years |
| Williams et al. [10] | Donor status (age) | Donor status (cause of death) | 10952 | Graft failure |
| Operative factors (graft size) | Operative factors (the impact of the surgeon) |
| Recipient factors (indication, glaucoma, number of previous ipsilateral grafts) | Recipient factors (age) |
| Inoue et al. [11] | Operative factors (operation time) | Donor status(age) | 271 | Graft failure |
| Recipient factors (age, lens status, transplant number) | Operative factors (graft size, suture technique) |
| Xiao and Xie [16] | Recipient factors (indication) | — | 151 | Endothelial decompensation |
| Lass et al. [28] | Donor status(age, sex) | Donor status (race, cause of death, history of diabetes) | 567 | Endothelial cell loss at 5 years |
| Operative factors (graft size) | Operative factors (method of retrieval, death to preservation time) |
| Recipient factors (age, race, sex, indication, glaucoma) |
| Lass et al. [31] | Donor status (age, preoperative donor ECD) | Recipient factors (age) | 176 | ECD at 10 years |
| Operative factors (graft size) |
| Bertelmann et al. [37] | Recipient factors (glaucoma) | Donor status (age, preoperative donor ECD) | 293 | Endothelial cell loss at 36 months |
| Recipient factors (indication) |
| Wakefield et al. [38] | — | Donor status (age, preoperative donor ECD) | 9415 | Endothelial failure at 5 years |
| Yu et al. [39] | Donor status (age, preoperative donor ECD) | Donor status (sex, race, cause of death, history of diabetes) | 377 | Graft failure |
| Recipient factors (age, indication, glaucoma) | Operative factors (death to preservation time, storage time) |
| Recipient factors (race, sex, laterality) |
| Armitage et al. [40] | Donor status (sex) | Donor status (age, preoperative donor ECD) | 3014 | Graft failure at 5 years |
| Operative factors (postoperative surgical procedures, donor/recipient trephine difference) | Operative factors (graft size, death to preservation time, storage time, suturing method) |
| Recipient factors (indication, glaucoma, infection) | Recipient factors (age, donor-recipient age difference, sex) |
| Sugar et al. [41] | Recipient factors (indication, glaucoma) | Operative factors (graft size) | 1090 | Graft failure at 5 years |
| Recipient factors (age, sex, diabetes, smoking) |
| Sugar et al. [42] | — | Donor status (sex, cause of death, history of diabetes, preoperative donor ECD) | 1090 | Graft failure at 5 years |
| Operative factors (method of retrieval, death to preservation time, endothelial cell damage |
| Descemet folds, epithelial defects) |
| Gal et al. [43] | — | Donor status (age) | 1090 | Graft failure at 5 years |
| Borderie et al. [44] | Donor status (age, preoperative donor ECD) | — | 231 | Graft failure at 1 year and ECD at 2 years |
| Operative factors (graft size, storage time) |
| Recipient factors (age, indication, glaucoma) |
| Chung et al. [45] | Operative factors (graft size) | — | 90 | ECD at 2 years |
| Recipient factors (indication) |
| Szentmary et al. [46] | Operative factors (the impact of the surgeon) | 370 | ECD |
|
