Association of Optic Neuritis with CYP4F2 Gene Single Nucleotide Polymorphism and IL-17A Concentration

Table 2

Frequency of CYP4F2 rs1558139 genotypes and alleles in patients with optic neuritis (ON) and in control group.

Gene	Genotype/allele	Frequency (%)
		Control group; n (%)	HWE	ON group; n (%)	HWE	value
CYP4F2; rs1558139	Genotype
	G/G	50 (30.5)	0.481	14 (35)	0.616
	G/A	77 (47)		18 (45)
	A/A	37 (22.5)		8 (20)
	Total	164 (100)		40 (100)
	Allele
	G	177 (54.0)		46 (57.5)
	A	151 (46.0)		34 (42.5)

ON: optic neuritis; value: significance level (alpha = 0.05); value HWE: significance level (alpha = 0.05) by Hardy–Weinberg equilibrium.