Association of Optic Neuritis with CYP4F2 Gene Single Nucleotide Polymorphism and IL-17A Concentration

Table 4

Frequency of CYP4F2 rs1558139 genotypes and alleles in the groups of optic neuritis (ON) patients with and without MS by gender.

Gene	Genotype/allele	Frequency (%)
		ON without MS group; n (%)		value	ON with MS group; n (%)		value
		Women	Men		Women	Men
CYP4F2; rs1558139	Genotype
	G/G	3 (27)	1 (14.3)	1.000	6 (32.1)	4 (66.7)	0.362
	G/A	9 (75)	2 (28.6)	0.074	5 (53.6)	2 (33.3)	1.000
	A/A	0 (0)	4 (57.1)	0.009	4 (14.3)	0 (0)	0.281
	Total	12 (100)	7 (100)		15 (100)	6 (100)
	Allele
	G	15 (62.5)	4 (28.6)	0.044	17 (56.7)	10 (83.33)	0.158
	A	9 (37.5)	10 (71.4)		13 (43.3)	2 (16.67)

ON: optic neuritis; MS: multiple sclerosis: value: significance level (alpha = 0.05).