Clinical Study

Early Changes in Visual Quality and Corneal Structure after DMEK: Does DMEK Approach Optical Quality of a Healthy Cornea?

Table 1

Visual function parameters in patients undergoing DMEK as measured preoperative and at 1 month and at 6 months postoperative.

Functional parameterPreoperative1 month postoperativeP (preoperative vs 1 month postoperative)6 month postoperativeP (1 month vs 6 months postoperative)

Visual Acuity
VA ETDRS photopic0.59 (0.33)0.31 (0.19)0.0130.13 (0.09)0.008
VA ETDRS mesopic0.75 (0.25)0.50 (0.22)0.0120.36 (0.15)0.130

Contrast sensitivity
CSV 3cpd0.46 (0.52)1.06 (0.61)0.0051.49 (0.45)0.077
CSV 6cpd0.23 (0.52)1.17 (0.65)<0.0011.33 (0.47)0.363
CSV12cpd0.21 (0.41)0.58 (0.50)0.0310.80 (0.46)0.217
CSV18cpd0.08 (0.18)0.29 (0.31)0.0150.45 (0.46)0.264
CSV-M 3cpd0.44 (0.48)1.20 (0.48)0.0011.52 (0.28)0.056
CSV-M 6cpd0.19 (0.44)1.19 (0.55)<0.0011.26 (0.66)0.401
CSV-M 12cpd0.13 (0.31)0.71 (0.67)0.0040.76 (0.56)0.741
CSV-M 18cpd0.07 (0.18)0.23 (0.30)0.0220.34 (0.28)0.350
CSV-MG 3cpd0.21 (0.45)1.06 (0.58)0.0011.46 (0.33)0.034
CSV-MG 6cpd0.12 (0.35)0.83 (0.57)<0.0010.84 (0.64)0.867
CSV-MG 12cpd0.04 (0.15)0.43 (0.39)0.0010.59 (0.56)0.434
CSV-MG 18cpd0.05 (0.35)0.27 (0.33)0.0020.34 (0.28)0.755
Pelli-Robson1.00 (0.29)1.29 (0.18)0.0051.48 (0.14)0.006

P values correspond to comparisons preoperative versus 1 month and 1 month versus 6 months. Bold letters indicate . Asterisks mark Bonferroni values less than 0.003. DMEK, Descemet membrane endothelial keratoplasty; VA, visual acuity; ETDRS, Early Treatment Diabetic Retinopathy Study; CSV, contrast sensitivity vision; cpd, cycles per degree.