The Association between Female Reproductive Factors and Open-Angle Glaucoma in Korean Women: The Korean National Health and Nutrition Examination Survey V

Table 3

Multivariate logistic regression analyses for the association between open-angle glaucoma and age at menarche, early menopause, and parity.

		All		Natural menopause
		OR (95% CI)	value	OR (95% CI)	value
Age at menarche, years
13–16 years	Model I	Reference	0.506	Reference	0.397
≤12 years		0.99 (0.45–2.15)		1.10 (0.40–3.02)
≥17 years		0.83 (0.60–1.14)		0.79 (0.56–1.13)
13–16 years	Model II	Reference	0.425	Reference	0.279
≤12 years		1.01 (0.38–2.65)		1.10 (0.39–3.15)
≥17 years		0.80 (0.56–1.13)		0.75 (0.52–1.09)
Early menopause <45 years
	Model I	1.50 (0.96–2.34)	0.073	2.05 (1.22–3.50)	0.009
	Model II	1.60 (0.94–2.73)	0.082	2.28 (1.17–4.46)	0.016
Parity
	Model I	1.03 (0.97–1.09)	0.415	1.02 (0.96–1.08)	0.556
	Model II	1.02 (0.95–1.10)	0.631	1.02 (0.94–1.11)	0.686

CI = confidence interval. Model I, adjusted for age, diabetes mellitus, hypertension, myopia, body mass index, oral contraceptive use, and hormone replacement. Model II, adjusted for age, diabetes mellitus, hypertension, myopia, body mass index, oral contraceptive use, hormone replacement, and female reproductive factors (age at menarche, early menopause, lactation history, and parity).