Review Article
The Role of Dll4/Notch Signaling in Normal and Pathological Ocular Angiogenesis: Dll4 Controls Blood Vessel Sprouting and Vessel Remodeling in Normal and Pathological Conditions
Figure 6
Pharmacological inhibition of Dll4 in OIR using soluble Dll4-Fc fusion protein (b) ameliorates pathological retinal neovascularization and improves normal retinal revascularization in the OIR model [33]. Yellow arrows indicate pathological neovascular tufts.
(a) |
(b) |