Review Article

The Role of Dll4/Notch Signaling in Normal and Pathological Ocular Angiogenesis: Dll4 Controls Blood Vessel Sprouting and Vessel Remodeling in Normal and Pathological Conditions

Figure 6

Pharmacological inhibition of Dll4 in OIR using soluble Dll4-Fc fusion protein (b) ameliorates pathological retinal neovascularization and improves normal retinal revascularization in the OIR model [33]. Yellow arrows indicate pathological neovascular tufts.
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