Research Article

Vascular Endothelial Growth Factor (VEGF) Serological and Lacrimal Signaling in Patients Affected by Vernal Keratoconjunctivitis (VKC)

Table 1

Demographics and clinical grading of 21 vernal keratoconjunctivitis (VKC) patients.

Characteristics of VKC patients

Sex16 males (76%)5 females (24%)
Age (from 6 to 16 years)Mean 8.62SD ± 2.65
VA (BCVA)20/20SD ± 0.0
Atopic SPT11 positive (52.4%); major allergens: house dust and grasses10 negative (47.6%)
Family condition12 (57%) familiar with allergic DS3 (14%) familiar with autoimmune DS
VKC formsTarsal: 13 (62%)Mixed: 8 (38%)
Vitamin D levels (VKC vs controls) (in ng/ml)19.8 ± 6.7 vs 24.7 ± 6.5Lower levels if compared to controls ()


ANA positivity30.8%Total IgE 4100 UI/ml46.1%
Photophobia (grade 4)42.3%Secretion or tearing28.8%
Foreign body sensation25.4%Itching and conjunctival hyperemia11.5%

SD: standard deviation; VA: visual acuity; BCVA: best-corrected visual acuity for far distance; SPT: skin prick test for several common inhalants and food allergens; DS: diseases.