Vascular Endothelial Growth Factor (VEGF) Serological and Lacrimal Signaling in Patients Affected by Vernal Keratoconjunctivitis (VKC)
Table 1
Demographics and clinical grading of 21 vernal keratoconjunctivitis (VKC) patients.
Characteristics of VKC patients
Sex
16 males (76%)
5 females (24%)
Age (from 6 to 16 years)
Mean 8.62
SD ± 2.65
VA (BCVA)
20/20
SD ± 0.0
Atopic SPT
11 positive (52.4%); major allergens: house dust and grasses
10 negative (47.6%)
Family condition
12 (57%) familiar with allergic DS
3 (14%) familiar with autoimmune DS
VKC forms
Tarsal: 13 (62%)
Mixed: 8 (38%)
Vitamin D levels (VKC vs controls) (in ng/ml)
19.8 ± 6.7 vs 24.7 ± 6.5
Lower levels if compared to controls ()
ANA positivity
30.8%
Total IgE 4100 UI/ml
46.1%
Photophobia (grade 4)
42.3%
Secretion or tearing
28.8%
Foreign body sensation
25.4%
Itching and conjunctival hyperemia
11.5%
SD: standard deviation; VA: visual acuity; BCVA: best-corrected visual acuity for far distance; SPT: skin prick test for several common inhalants and food allergens; DS: diseases.