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Journal of Ophthalmology
Volume 2018 (2018), Article ID 4081874, 4 pages
Research Article

Anatomical Retinal Changes after Photodynamic Therapy in Chronic Central Serous Chorioretinopathy

1Department of Ophthalmology, Gregorio Marañón University General Hospital, Madrid, Spain
2IIS-Aragón, Department of Ophthalmology, Miguel Servet University Hospital, Zaragoza, Spain
3University of Zaragoza, Zaragoza, Spain

Correspondence should be addressed to Pilar Calvo

Received 20 October 2017; Revised 4 January 2018; Accepted 9 January 2018; Published 6 February 2018

Academic Editor: Luca Di Antonio

Copyright © 2018 María Pilar Ruiz-del-Tiempo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To evaluate anatomical retinal changes measured by spectral-domain optical coherence tomography (SD-OCT), after applying photodynamic therapy (PDT) for treatment of chronic central serous chorioretinopathy (CSC). Methods. A retrospective analysis was conducted on 43 patients (48 eyes) with chronic CSC treated with PDT. Visual acuity (VA), central retinal thickness (CRT), outer nuclear layer (ONL) thickness, subretinal fluid (SRF), and photoreceptor ellipsoid zone (EZ) measured by SD-OCT were collected at baseline and at 3, 6, and 12 months after PDT. Differences between normally distributed variables were calculated by a paired-sample t-test; was considered statistically significant. Results. Mean age was 50 ± 9.8 years. Mean time from diagnosis to PDT was 12.5 months. Baseline VA was 0.51 ± 0.24 and significantly improved () to 0.74 ± 0.26 one year after PDT. CRT and SRF significantly decreased () at 3, 6, and 12 months after treatment. ONL thickness and EZ did not significantly change at any point during follow-up. Conclusions. Not significant changes were found in the ONL or EZ 12 months after PDT.