Predictive Factors for Successful Type 1 Big Bubble during Deep Anterior Lamellar Keratoplasty

Table 2

Characteristics of patients and surgical procedures.

Variable	Overall ()		Type 1 big bubble ()	No type 1 big bubble ()	value
	Mean/number	Range/percentage	Mean/number	Mean/number
Patient age (years)	37.9	[13; 77]	39.3	36.6	0.43
Preoperative diagnosis:					0.0002
Keratoconus and other ectatic disorders	62	80.5%	27	35
Scar after infectious keratitis	6	7.8%	4	2
Stromal dystrophy	6	7.8%	5	1
Scar after trauma	2	2.6%	2	0
Stromal opacification after penetrating Keratoplasty	1	1.3%	0	1
Preoperative best-corrected LogMAR visual acuity	1.23	[0.5; 2.3]	1.21	1.24	0.81
OCT central epithelial thickness (µm)	49	[38; 66]	49	49	0.89
OCT minimal epithelial thickness (µm)	29	[8; 55]	30	28	0.57
OCT central corneal thickness (µm)	418	[144; 682]	425	412	0.59
Keratoconus OCT classification (Table 1):					0.0001
Stage 1	3	4.8%	1	2
Stage 2	13	21.0%	7	6
Stage 3	22	35.5%	17	5
Stage 4	23	37.1%	2	21
Stage 5	1	1.6%	0	1
Scar in posterior stroma:					0.0002
Yes	28	36.4%	6	22
No	49	63.6%	32	17
Scar in midstroma:					0.12
Yes	52	67.5%	23	29
No	25	32.5%	15	10
Scar in anterior stroma:					0.72
Yes	70	90.9%	35	35
No	7	9.1%	3	4
Maximal-minimal corneal thickness > 220 µm ():					0.13
Yes	43	57.3%	18	25
No	32	42.7%	19	13
Preoperative recipient corneal endothelial cell density (cells/mm^2)	2654	[1000; 3450]	2631	2689	0.75
Trephination diameter (mm)	8.17	[7.5; 8.5]	8.18	8.17	0.74
Trephination depth (µm)	421	[250; 550]	435	408	0.03

OCT: optical coherence tomography. Data were available for the 77 patients unless indicated.