In Vivo Confocal Microscopic Observations of Vortex Keratopathy in Patients with Amiodarone-Induced Keratopathy and Fabry Disease

Figure 2

In vivo confocal microscopic findings of the right eye of case 1 at 39 days (a), 128 days (b), and 194 days (c) after beginning the amiodarone application. The corneal basal epithelial cell layers from the center (1), paracentral (2), and peripheral (3) cornea (circles) are shown. (a, 1) Clusters of epithelial cells with highly reflective cytoplasm can be seen at the center of cornea. (a, 2) Sparsely clustered highly reflective epithelial cells can be seen at the paracentral cornea. (a, 3) No highly reflective epithelial cells are observed at the peripheral cornea. (b, 1; b, 2) Clusters of epithelial cells with a highly reflective cytoplasm can be seen at the center (b, 1) and paracentral (b, 2) cornea, and the clusters are often seen aligned. (b, 3) Sparsely clustered highly reflective epithelial cells are observed at the peripheral cornea. (c) Clusters of epithelial cells with a highly reflective cytoplasm can be seen at the center (c, 1), paracentral (c, 2) and peripheral (c, 3) cornea, and the clusters are often aligned.

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