Manifestation of Clinical Categories of Ocular Graft-versus-Host Disease

Figure 3

Typical ocular signs of ocular GVHD. (a)–(f) Signs of acute ocular GVHD and differential diagnosis: (a) mucus secretion (arrow) and conjunctival injection of acute ocular GVHD; (b) mucus secretion using fluorescein dye and visualized under a cobalt blue light; (c) and (d) conjunctiva and cornea signs of mild acute ocular GVHD; (e) and (f) conjunctiva and cornea signs of a post allo-HSCT patient who complained of red eye, lacrimation, and increased eye discharge and was diagnosed with viral corneal dermatitis eventually. (g)–(k) Signs and complications of chronic ocular GVHD: (g) and (h) typical fibrous secretion (arrow) of chronic ocular GVHD; (i) filamentary keratitis; (j) corneal perforation; and (k) corneal vascularization.