Research Article

Manifestation of Clinical Categories of Ocular Graft-versus-Host Disease

Table 2

Outcomes of objective ocular examinations of two groups.

OutcomesAcute GVHDChronic GVHD
(, eyes = 42)(, eyes = 254)

Best corrected visual acuity (logMAR)
 Mean ± SD0.23 ± 0.240.24 ± 0.27
Z−0.165
(Mann–Whitney U test)0.869

Intraocular pressure (mmHg)
 Mean ± SD13.42 ± 2.0414.11 ± 2.70
Z−1.566
(Mann–Whitney U test)0.117

Corneal fluorescein staining
 Mean ± SD2.5 ± 3.85.8 ± 3.9
Z−5.726
(Mann–Whitney U test)<0.001

Schirmer tear secretion score (mm)
 Mean ± SD9.0 ± 3.62.8 ± 2.0
Z−9.623
(Mann–Whitney U test)<0.001

Fluorescein tear film break-up time (seconds)
 Mean ± SD5.7 ± 3.63.2 ± 2.7
Z−4.054
(Mann–Whitney U test)<0.001

GVHD = graft-versus-host disease.