Spectral Domain Optical Coherence Tomography Assessment of Macular and Optic Nerve Alterations in Patients with Glaucoma and Correlation with Visual Field Index

Table 1

Mann–Whitney and AUC of the parameters with the highest diagnostic ability in the CTRL vs. IG, CTRL vs. AG, and IG vs. AG comparisons.

CTRL vs. IG			CTRL vs. AG			IG vs. AG
Parameter	AUC	value	Parameter	AUC	value	Parameter	AUC	value
Macula GCL mean inner	0.9	4.29449E − 06	Macula GCL mean inner	1.0	3.94592E − 10	Macula GCL mean inner	0.9	9.29422E − 06
Macula GCL mean outer	0.9	2.3797E − 06	Macula GCL mean outer	1.0	3.11259E − 10	Macula GCL mean outer	0.9	4.87372E − 07
Macula GCL temporal inner	0.9	6.40501E − 07	Macula GCL temporal inner	1.0	3.59673E − 10	Macula GCL temporal inner	0.9	3.5386E − 06
Macula GCL temporal outer	0.9	2.26545E− 07	Macula GCL temporal outer	1.0	1.6719E − 10	Macula GCL temporal outer	0.9	4.12819E − 06
Macula IPL temporal inner	0.9	4.81767E − 06	Macula IPL temporal inner	1.0	1.67747E − 10	Macula IPL temporal inner	0.9	1.42929E − 05
Macula RNFL mean outer	0.9	1.6614E − 05	Macula RNFL mean outer	1.0	4.46656E − 10	Macula RNFL mean outer	0.9	3.41429E − 06
Macula mean GCL	0.9	9.86195E − 07	Macula mean GCL	1.0	1.78465E − 10	Macula mean GCL	0.9	1.04181E − 06
Macula mean RNFL	0.9	2.51857E − 06	Macula mean RNFL	1.0	3.14624E − 10	Macula mean RNFL	0.9	9.886E − 07
cpRNFL global	0.9	3.19772E − 06	cpRNFL global	1.0	2.68425E − 10	cpRNFL global	0.9	7.41664E − 07
cpRNFL temporal superior	0.9	2.83685E − 06	cpRNFL temporal superior	1.0	2.70908E − 10	cpRNFL temporal superior	0.9	4.33798E − 06
VFI	0.9	2.14775E − 06	VFI	1.0	3.81295E − 11	VFI	1.0	6.5955E − 09

GCL: ganglion cell layer; IPL: inner plexiform layer; cpRNFL: circumpapillary retinal nerve fiber layer thickness; VFI: visual field index; CTRL: control group; IG: Early Glaucoma Group; AG: Advanced Glaucoma Group; value Mann–Whitney <0.05.