Ability of Swept-Source Optical Coherence Tomography to Detect Retinal and Choroidal Changes in Patients with Multiple Sclerosis
Table 2
Peripapillary retinal and ganglion cell layer thickness as measured with swept-source deep range imaging optical coherence tomography Triton in patients with multiple sclerosis and healthy subjects.
Peripapillary measurements
Healthy controls
MS
Retinal thickness
Total
291.87 (15.32)
277.75 (16.86)
<0.001
Quadrants (x4)
Superior
310.03 (21.53)
292.81 (24.05)
<0.001
Nasal
262.33 (16.02)
259.02 (14.72)
0.129
Inferior
313.45 (21.19)
292.03 (21.51)
<0.001
Temporal
281.53 (12.80)
267.10 (16.70)
<0.001
Sectors (x6)
Superonasal
302.64 (27.51)
284.88 (27.06)
<0.001
Superotemporal
321.31 (20.46)
303.05 (25.56)
<0.001
Nasal
267.47 (16.33)
262.17 (14.60)
0.016
Inferonasal
310.43 (26.81)
289.10 (27.09)
<0.001
Inferotemporal
323.19 (21.25)
300.61 (23.25)
<0.001
Temporal
281.53 (12.80)
267.10 (16.70)
<0.001
RNFL thickness
Total
104.74 (11.38)
94.60 (14.40)
<0.001
Quadrants (x4)
Superior
126.03 (18.03)
112.39 (19.36)
<0.001
Nasal
76.51 (11.02)
78.97 (14.04)
0.166
Inferior
139.40 (19.71)
120.23 (20.99)
<0.001
Temporal
76.93 (12.43)
66.79 (16.64)
<0.001
Sectors (x6)
Superonasal
117.01 (25.30)
101.49 (21.42)
<0.001
Superotemporal
138.00 (18.35)
124.48 (24.93)
<0.001
Nasal
83.12 (12.00)
83.25 (14.12)
0.966
Inferonasal
138.63 (27.54)
119.83 (28.49)
<0.001
Inferotemporal
147.17 (22.60)
126.31 (26.18)
<0.001
Temporal
76.93 (12.43)
66.79 (16.64)
<0.001
GCL + thickness
Total
43.20 (4.06)
41.21 (3.60)
<0.001
Quadrants (x4)
Superior
40.72 (5.39)
39.49 (4.29)
0.076
Nasal
40.96 (4.36)
38.96 (5.15)
0.003
Inferior
38.81 (5.39)
37.16 (5.73)
0.036
Temporal
52.31 (7.02)
49.20 (6.03)
0.001
Sectors (x6)
Superonasal
41.94 (6.29)
41.37 (4.93)
0.481
Superotemporal
39.98 (7.54)
38.29 (6.01)
0.083
Nasal
40.46 (4.32)
38.53 (4.80)
0.003
Inferonasal
37.51 (6.36)
35.57 (7.29)
0.045
Inferotemporal
40.39 (7.03)
38.91 (7.10)
0.139
Temporal
52.31 (7.02)
49.20 (6.03)
0.001
Numbers indicate mean values with standard deviation between brackets. Bold letters indicate statistical significance. Significant values after Bonferroni correction for multiple comparisons; MS, multiple sclerosis; RNFL, retinal nerve fiber layer; GCL, ganglion cell layer.
