Effects of Oral Supplementation with Docosahexaenoic Acid (DHA) plus Antioxidants in Pseudoexfoliative Glaucoma: A 6-Month Open-Label Randomized Trial

Table 1

Composition of BrudyPio 1.5 g (Brudy Lab S.L., Barcelona, Spain) per capsule.

Composition	Per capsule	% recommended daily amount in one capsule	Per three capsules	% recommended daily amount in three capsules
Concentrated oil in ω-3 fatty acids (mg)	500		1,500
TG-DHA 70%	350	—	1,050	—
EPA 8.5%	42.5	—	127.5	—
DPA 6%	30	—	90	—
Vitamins
Vitamin A (retinol, µg)	133.3	17	400	50
Vitamin C (ascorbic acid, mg)	26.7	33	80	100
Vitamin E (d-α-tocopherol, mg)	4	33	12	100
Vitamin B1 (thiamine, mg)	0.36	33	1.1	100
Vitamin B2 (riboflavin, mg)	0.46	33	1.4	100
Vitamin B3 (niacin equivalent, mg)	5.33	33	16	100
Vitamin B6 (pyridoxine, mg)	0.46	33	1.4	100
Vitamin B9 (folic acid, µg)	66.7	33	200	100
Vitamin B12 (cobalamin, µg)	0.83	33	2.5	100
Essential trace elements
Zinc, mg	3.33	33	10	100
Copper, mg	0.33	33	1	100
Selenium, µg	18.3	33	55	100
Manganese, mg	0.66	33	2	100
Other components
Lutein, mg	3.33	—	10	—
Zeaxanthin, mg	0.33	—	1	—
Glutathione, mg	2	—	6	—
Lycopene, mg	2	—	6	—
Coenzyme Q10, mg	2	—	6	—
Anthocyanins, mg	5	—	15	—
Oleuropein, µg	67	—	200	—

TG-DHA: triglyceride-bound DHA; EPA: eicosapentaenoic acid; DPA: docosapentaenoic acid. Note: The dosage is tested is three capsules per day, which corresponds to 100% of the recommended daily amounts of the included vitamins and minerals.