Clinical Study
Effects of Oral Supplementation with Docosahexaenoic Acid (DHA) plus Antioxidants in Pseudoexfoliative Glaucoma: A 6-Month Open-Label Randomized Trial
Table 2
Baseline characteristics of the study patients.
| | Variables | Total patients () | Study group | value | | Experimental () | Control () |
| | Men/women | 25/22 | 11/12 | 14/10 | 0.470 | | Age, years, mean (SD) | 70.3 (5.0) | 70.7 (4.5) | 69.9 (5.6) | 0.563 |
| | Comorbid diseases | — | — | — | — | | Hypertension | 19 | 10 | 9 | — | | Dyslipidemia | 21 | 10 | 11 | — | | Diabetes mellitus | 4 | 2 | 2 | — | | Chronic obstructive pulmonary disease | 6 | 2 | 4 | — | | Osteoporosis | 5 | 2 | 3 | — | | Ischemic heart disease | 2 | 2 | — | — | | Depression | 2 | — | 2 | — | | Arthrosis | 2 | 1 | 1 | — |
| | PEX glaucoma | — | — | — | 0.765 | | Right eye | 14 (29.8) | 7 (30.4) | 7 (29.2) | — | | Left eye | 13 (27.6) | 5 (21.7) | 7 (29.2) | — | | Both eyes | 21 (44.7) | 11 (47.8) | 10 (41.7) | — | | BCVA, decimals, mean (SD) | — | — | — | — |
| | Right eye | 0.90 (0.19) | 0.91 (0.22) | 0.89 (0.16) | 0.735 | | Left eye | 0.86 (0.21) | 0.87 (0.19) | 0.85 (0.22) | 0.776 |
| | IOP, mmHg, mean (SD) | — | — | — | — | | Right eye | 14.8 (3.5) | 14.7 (3.3) | 15.0 (3.7) | 0.769 | | Left eye | 14.9 (4.2) | 15.1 (3.3) | 14.7 (4.9) | 0.732 |
| | Central corneal thickness, µm, mean (SD) | — | — | — | — | | Right eye | 535.9 (38.6) | 543.2 (36.6) | 529.0 (40.0) | 0.214 | | Left eye | 535.5 (37.5) | 540.1 (36.0) | 531.1 (39.0) | 0.416 |
| | RNFLT, µm, mean (SD) | — | — | — | — | | Right eye | 67.8 (22.1) | 67.2 (20.5) | 68.3 (23.8) | 0.880 | | Left eye | 74.5 (19.2) | 71.7 (16.4) | 76.7 (21.2) | 0.416 |
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PEX: pseudoexfoliative; BCVA: best corrected visual acuity; IOP: intraocular pressure; RNFLT: retinal nerve fiber layer thickness.
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