Combined Application of Bevacizumab and Mitomycin C or Bevacizumab and 5-Fluorouracil in Experimental Glaucoma Filtration Surgery

Figure 6

Bleb photograph examples in rabbit subconjunctival scar models 20 days after the surgery. Compared with the control group (a), 5-fluorouracil (5-Fu) treatment group (b) had a nearly normal distribution of blood vessels with filtering blebs low and flat. Compared with the control group (a), bevacizumab (BVZ) treatment (c) and 5-Fu + BVZ groups (e) showed slightly higher and diffused filtering blebs, and the distribution of blood vessels was not obvious. Compared with the control group (a), mitomycin C (MMC) (d) and MMC + BVZ groups (f) showed more conjunctival blood vessels with obviously bulged filtering blebs.

(a)

(b)

(c)

(d)

(e)

(f)