Research Article

DNA Methylation Status of the Interspersed Repetitive Sequences for LINE-1, Alu, HERV-E, and HERV-K in Trabeculectomy Specimens from Glaucoma Eyes

Table 3

Alu methylation levels in glaucoma eyes and control eyes.

% mC% mCmC% mCuC% uCmC% uCuC

Normal control1052.8278 ± 0.592625.1117 ± 1.294827.5755 ± 2.297927.8567 ± 2.482419.4560 ± 0.1800
POAG1652.1945 ± 0.691624.0020 ± 1.587527.5126 ± 2.201428.8725 ± 0.460019.6130 ± 0.3089
PACG1251.4995 ± 1.388422.6191 ± 2.754228.8866 ± 2.780728.8743 ± 0.339519.6201 ± 0.2302
Secondary glaucoma1651.9548 ± 0.971223.5236 ± 1.926827.9738 ± 2.078428.8885 ± 0.424119.6140 ± 0.2888

All values are presented as mean ± standard deviation. % mC = percentage of Alu methylation; % mCmC = percentage of Alu hypermethylated loci number; % mCuC, % uCmC = percentage of Alu partially methylated loci; % uCuC = percentage of Alu hypomethylated loci number.