Neurodegeneration in Patients with Type 2 Diabetes Mellitus without Diabetic Retinopathy
Table 4
Structural measurements obtained with Spectralis OCT in patients with type 2 diabetes mellitus with disease duration of <10 and ≥10 years, respectively.
Disease duration <10 years
Disease duration ≥10 years
Mean
SD
Mean
SD
Macular thickness
Central
274.77
16.12
276.11
20.94
0.798
Inner superior
338.91
13.57
333.34
15.22
0.161
Inner nasal
339.64
15.13
336.68
16.07
0.487
Inner inferior
334.27
13.22
330.16
15.60
0.303
Inner temporal
327.09
10.51
321.26
16.54
0.143
Outer superior
298.45
12.53
288.11
14.71
0.008
Outer nasal
309.45
13.23
306.11
14.91
0.386
Outer inferior
282.95
12.05
277.21
15.12
0.133
Outer temporal
286.82
11.24
276.26
14.15
0.004
pRNFL Glaucoma
Average
98.91
9.77
94.21
13.08
0.149
Superior
123.36
15.85
116.43
20.92
0.184
Nasal
73.36
12.53
71.97
16.16
0.730
Inferior
130.52
16.29
119.99
19.43
0.036
Temporal
68.18
11.18
68.24
8.95
0.983
Superotemporal
140.09
19.21
127.47
22.03
0.029
Inferotemporal
143.73
15.05
130.11
21.63
0.012
Superonasal
106.64
20.03
105.39
24.65
0.842
Inferonasal
117.32
27.17
109.87
21.54
0.246
pRNFL Axonal Analytics
Average
100.23
10.07
95.32
13.20
0.137
Superior
127.66
17.14
115.84
18.79
0.019
Nasal
76.27
13.61
73.11
16.38
0.447
Inferior
130.16
16.33
122.80
21.80
0.175
Temporal
66.95
10.62
69.26
11.20
0.436
Superonasal
112.68
21.97
104.55
20.68
0.157
Inferonasal
118.82
27.70
112.24
23.00
0.326
Superotemporal
142.64
21.07
127.13
21.10
0.008
Inferotemporal
141.50
14.36
133.37
23.80
0.151
Papillomacular bundle
51.05
8.39
54.55
8.10
0.116
Nasal/temporal index
1.16
0.26
1.08
0.31
0.301
Bold letters indicate . Asterisks mark significant values according to Bonferroni corrections for multiple comparisons. DM2, type 2 diabetes mellitus; pRNFL: peripapillary Rretinal nerve fiber layer; SD, standard deviation.
