Neurodegeneration in Patients with Type 2 Diabetes Mellitus without Diabetic Retinopathy
Table 5
Structural measurements obtained with Spectralis optical coherence tomography in patients with type 2 diabetes mellitus, with and without vascular complications.
Without complications
With complications
Mean
SD
Mean
SD
Macular thickness
Central
278.23
15.19
270.76
24.68
0.152
Inner superior
336.41
13.48
333.48
17.11
0.468
Inner nasal
338.87
15.04
335.71
16.95
0.461
Inner inferior
332.49
15.11
330.14
14.41
0.563
Inner temporal
323.90
14.89
322.48
14.93
0.726
Outer superior
291.49
14.86
292.67
14.82
0.770
Outer nasal
306.74
14.65
308.43
13.90
0.667
Outer inferior
280.00
15.68
278.05
11.36
0.617
Outer temporal
278.85
14.11
282.52
13.89
0.337
pRNFL Glaucoma
Average
97.36
14.27
93.29
5.80
0.217
Superior
121.78
22.13
113.76
11.53
0.127
Nasal
72.79
16.01
71.90
12.71
0.827
Inferior
124.49
22.29
122.67
10.40
0.725
Temporal
70.18
9.95
64.57
8.36
0.032
Superotemporal
135.15
24.58
126.43
14.02
0.140
Inferotemporal
135.54
23.83
134.29
12.34
0.823
Superonasal
108.41
24.43
101.10
19.39
0.241
Inferonasal
113.44
26.71
111.05
17.68
0.714
pRNFL Axonal Analytics
Average
98.59
14.51
94.38
5.78
0.208
Superior
122.86
21.36
115.19
12.35
0.136
Nasal
74.54
16.64
73.76
13.08
0.854
Inferior
125.86
23.62
124.83
11.65
0.853
Temporal
70.82
11.14
63.95
9.28
0.019
Superonasal
109.85
23.38
103.24
16.60
0.256
Inferonasal
114.85
27.77
114.29
18.68
0.934
Superotemporal
135.87
24.28
127.14
16.87
0.148
Inferotemporal
136.87
24.91
135.38
11.41
0.796
Papillomacular bundle
55.23
8.19
49.62
7.40
0.011
Nasal/temporal index
1.08
0.32
1.17
0.23
0.236
Bold letters indicate . Asterisks mark significant values according to Bonferroni corrections for multiple comparisons. DM2, type 2 diabetes mellitus; pRNFL: peripapillary retinal nerve fiber layer; SD, standard deviation.
