Journal of Ophthalmology

Research Article

Pulse Waveform Analysis of the Ocular Blood Flow Using Laser Speckle Flowgraphy before and after Glaucoma Treatment

Table 2

Changes in ocular and systemic parameters at 3 months after the instillation of topical prostaglandin analogs (N = 28).


	Before treatment	After treatment	value

IOP (mmHg)	15.95 ± 2.81	11.82 ± 2.31	0.001
MOPP (mmHg)	42.95 ± 12.48	46.25 ± 7.18	0.004
MBP (mmHg)	85.58 ± 13.15	87.70 ± 11.73	0.175
Heart rate (beats/min)	70.92 ± 12.57	69.90 ± 10.41	0.657
MBR_T (AU)	10.43 ± 1.65	10.10 ± 1.80 (97.2 ± 11.0)	0.136 (0.143)
Fluctuation (AU)	13.05 ± 3.44	12.23 ± 3.34 (94.8 ± 15.7)	0.106 (0.122)
BOS (AU)	77.39 ± 5.79	78.65 ± 5.89 (101.7 ± 4.8)	0.122 (0.116)
ATI (AU)	31.56 ± 3.58	30.44 ± 3.82 (96.7 ± 7.8)	0.034 (0.031)
BOT (AU)	51.81 ± 4.72	51.89 ± 4.75 (99.8 ± 6.2)	0.909 (0.982)
Skew (AU)	11.13 ± 1.94	11.34 ± 1.90 (102.9 ± 13.4)	0.301 (0.290)
Number of glaucoma medications	0	1	<0.001

The data are presented as means ± standard deviations. Differences in values before and after treatment were determined using analysis of variance with the Wilcoxon test. The ratios calculated based on the pretreatment values and values based on the ratios were presented in the square brackets. IOP: intraocular pressure; MOPP: mean ocular perfusion pressure; MBP: mean blood pressure; MBR_T: mean blur rate in the tissue area of the optic disc; AU: arbitrary unit; BOS: blowout score; ATI: acceleration time index; BOT: blowout time.