Journal of Ophthalmology / 2019 / Article / Tab 2

Research Article

Trabeculectomy and EX-PRESS Implantation in Open-Angle Glaucoma: An Updated Meta-Analysis of Randomized Controlled Trials

Table 2

Subgroup analysis of IOPR% from the baseline to the endpoint comparing trabeculectomy and EX-PRESS.

GroupNo. of studiesMDTest for heterogeneityTest for overall effect
EstimateLowerUpχ2I2 (%)Z

All83.60−3.1110.3114.49520.041.050.29
Follow-up
 ≤24 months55.23−3.5013.9610.96640.031.170.24
 >24 months30.23−9.159.601.8200.400.050.96
Sample size (each group)
 ≤30411.526.1416.892.7500.434.20<0.0001
 >304−1.37−7.464.732.1000.550.440.66
Publication year
 Before 20143−0.56−7.446.311.4300.490.160.87
 After 201455.72−3.0014.447.91490.091.290.20
Mitomycin-C concentration
 <0.4 mg/ml34.14−5.5113.784.42550.110.840.40
 ≥0.4 mg/ml42.54−9.3814.467.60610.050.420.68
 Unknown1−3.37−29.5422.80.250.80

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