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Journal of Ophthalmology
Volume 2019, Article ID 2406547, 6 pages
Research Article

Effect of Hemodialysis on Anterior Chamber Angle Measured by Anterior Segment Optical Coherence Tomography

1Department of Ophthalmology, Hanyang University College of Medicine, Seoul, Republic of Korea
2Division of Nephrology, Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Republic of Korea

Correspondence should be addressed to Sang-Woong Han; and Mincheol Seong; ten.liamnah@67snddog

Received 11 October 2018; Revised 9 December 2018; Accepted 21 January 2019; Published 14 August 2019

Academic Editor: Anna Nowinska

Copyright © 2019 Yong Un Shin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To investigate the effect of hemodialysis (HD) on the anterior chamber angle by anterior segment optical coherence tomography (ASOCT) and other ophthalmologic parameters in patients with end-stage kidney disease (ESKD). Methods. A prospective observational study was performed on 20 patients who underwent HD for ESKD. Anterior chamber angle images were obtained by 16 mm line scan of ASOCT. The angle opening distance (AOD) and the trabecular-iris space area (TISA) were determined using the ImageJ program. Additional 12 mm horizontal and 9 mm vertical wide-field scans centered on the posterior pole were performed for the measurement of peripapillary retinal nerve fiber layer (pRNFL) thickness and macular ganglion cell-inner plexiform layer (mGCIPL) thickness. Changes in intraocular pressure (IOP), AOD, TISA, pRNFL thickness, and mGCIPL thickness before and after HD were statistically analyzed. Results. The IOP decreased significantly from 17.5 ± 3.4 before HD to 16.2 ± 2.3 after HD (). There was a statistically significant decrease in AOD 750 and TISA 750 ( and , respectively). AOD 500 and TISA 500 also decreased, which was almost statistically significant ( and , respectively). Mean pRNFL thickness and mGCIPL thickness did not show significant change after HD. Conclusion. We observed a significant decrease in IOP and anterior chamber angle measurements after HD. Our study suggests that HD can influence the anterior segment structure of eyes.