Response to Aflibercept Therapy in Three Types of Choroidal Neovascular Membrane in Neovascular Age-Related Macular Degeneration: Real-Life Evidence in the Czech Republic

Table 2

Mean change in ETDRS letters and CRT in micrometers from baseline for different types of CNV lesions during the first year of intravitreal aflibercept injection treatment.

Types of CNV	ETDRS letters			CRT (micrometers)
Weeks	16	32	48	16	32	48
Classic	6.9	5.1	6.9	119.6	86.6	130.1
Minimally classic	2.4	2.8	2.5	158.8	137.7	165.4
Occult	6.1	5.1	6.7	139.9	142.7	164.7

Classic CNV eyes showed the greatest letter gain in vision yet after the initial 3 aflibercept injections. Minimally classic CNV eyes showed a great decrease of CRT.