Research Article
Association between Central Serous Chorioretinopathy and Risk of Depression: A Population-Based Cohort Study
Table 1
Characteristics of the study subjects.
| Variable | CSC group, n = 25939 | Control group, n = 103756 | value | n (%) | n (%) |
| Age, year (mean ± SD) | 42.9 ± 12.3 | 42.9 ± 12.3 | 1.000 | Age, categorical | | | 1.000 | <40 | 10813 (41.7) | 43252 (41.7) | | 40–50 | 8386 (32.3) | 33544 (32.3) | | 50–60 | 4163 (16.0) | 16652 (16.0) | | 60–70 | 1677 (6.5) | 6708 (6.5) | | ≥70 | 900 (3.5) | 3600 (3.5) | | Gender | | | 1.000 | Male | 17751 (68.4) | 71004 (68.4) | | Female | 8188 (31.6) | 32752 (31.6) | | Charlson comorbidity index | | | 0.06 | <2 | 23265 (89.7) | 93470 (90.1) | | ≥2 | 2674 (10.3) | 10286 (9.9) | | Insurance cost | | | <0.0001 | <30000 NTD | 17034 (65.7) | 71364 (68.8) | | ≥30000 NTD | 8905 (34.3) | 32392 (31.2) | | Urbanization level | | | 0.27 | Urban | 5297 (20.4) | 21511 (20.7) | | Rural | 20642 (79.6) | 82245 (79.3) | | Hypertension | | | <0.0001 | Yes | 7626 (29.4) | 11711 (11.3) | | No | 18313 (70.6) | 92045 (88.7) | | Peptic ulcer | | | <0.0001 | Yes | 5508 (21,2) | 3277 (3.2) | | No | 20431 (78.8) | 100479 (96.8) | | Smoking | | | <0.0001 | Yes | 4699 (18.9) | 4259 (4,1) | | No | 21040 (81.1) | 99497 (95.9) | | Depression during the follow-up period | 1561 (6.0) | 4736 (4.6) | <0.0001 |
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SD indicates standard deviation, and NTD indicates New Taiwan Dollar.
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