Different Characteristics of Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein Antibody-Seropositive Male Optic Neuritis in China

Table 1

Demographic and clinical characteristics of the male Ab-ON’ cohort.

	Total	Percentage
Number of patients (eyes)	76 (132)
Age of onset, year
Mean	27.11 ± 16.74
Range	3–72
Follow-up, month
Mean ± SD	38.67 ± 38.78
Range	6–158
Experience
Bilateral attack	19	25.0
Unilateral attack	57	75.0
Serum antibodies status
Positive AQP4-Ab	32	42.1
Positive MOG-Ab	44	57.9
Optic disc edema	22	28.9
Ocular pain	47	61.8
Abnormal autoimmune antibody	18	23.7
Presenting BCVA
≤0.1	40	30.3
0.1–0.5	8	6.1
≥0.5	84	63.6
Treatment
IV methylprednisolone	73	96.1

AQP4, aquaporin-4; MOG, myelin oligodendrocyte glycoprotein; IV, intravenous; BCVA, best-corrected visual acuity.