Research Article

Factors Related to Superior and Inferior Hemifield Defects in Primary Open-Angle Glaucoma

Table 2

Comparison of clinical characteristics between the superior hemifield and inferior hemifield defect groups.

Superior visual field defect groupInferior visual field defect group value

Demographic factors
Age (years)54.33 ± 13.3158.85 ± 8.390.205
Sex: male/female15 (37.5%)/25 (62.5%)9 (33.3%)/18 (66.7%)0.727
Family history of glaucoma: yes/no9 (22.5%)/31 (77.5%)5 (18.5%)/22 (81.5%)0.694

Ocular factors
Visual acuity1.18 ± 0.061.19 ± 0.040.340
Spherical equivalent (D)−2.50 ± 2.78−2.87 ± 2.150.711
Untreated IOP (mmHg)15.57 ± 2.4014.66 ± 1.970.107
CCT (μm)524.13 ± 33.75529.48 ± 34.700.385
DH: presence/absence1 (7.5%)/39 (92.5%)2 (7.4%)/25 (92.6%)0.354
Disc area (mm2)2.07 ± 0.452.00 ± 0.420.544
cpRNFL thickness corresponding to the defective hemifield (μm)75.27 ± 8.0279.83 ± 12.140.050
mGCC thickness corresponding to the defective hemifield (μm)75.86 ± 9.4481.27 ± 6.250.003

Perimetric parameters
MD (dB)−3.30 ± 3.72−2.07 ± 1.730.609
PSD (dB)6.94 ± 4.815.90 ± 3.240.596
Average TD values corresponding to defective hemifield (dB)−6.51 ± 7.34−3.53 ± 2.530.371
Prevalence of defects within 10 degrees: yes/no39 (97.5%)/1 (2.5%)23 (85.2%)/4 (14.8%)0.081
Prevalence of defects within 5 degrees: yes/no22 (55.0%)/18 (45.0%)4 (14.8%)/23 (85.2%)0.001
Average TD values within 10 degrees corresponding to defective hemifield (C8) (dB)−8.02 ± 8.55−3.93 ± 4.990.066
Average TD values within 5 degrees corresponding to defective hemifield (C2) (dB)−6.09 ± 9.37−1.00 ± 5.160.002

Systemic factors
Hypertension: yes/no8 (20.0%)/32 (80.0%)7 (25.9%)/20 (74.1%)0.568
Diabetes mellitus: yes/no4 (10.0%)/36 (90.0%)3 (11.1%)/24 (88.9%)0.594

Continuous variables are expressed as N (percentage), mean ± SD, or percentage. Statistically significant differences between the superior hemifield defect group and inferior hemifield defect group () by the Mann–Whitney U-test for continuous variables or Fisher’s exact test for categorical data are indicated in bold. IOP: intraocular pressure, CCT: central corneal thickness, DH: disc hemorrhage, cpRNFL: circumpapillary retinal nerve fiber layer, mGCC: macular ganglion cell complex, MD: mean deviation, PSD: pattern standard deviation, and TD: total deviation.