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Journal of Ophthalmology
Volume 2019, Article ID 4731653, 6 pages
Clinical Study

Prospective Cohort Study on Refractive Changes after Trabeculectomy

Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan

Correspondence should be addressed to Masaru Inatani;

Received 29 January 2019; Accepted 19 July 2019; Published 7 August 2019

Academic Editor: Luca Agnifili

Copyright © 2019 Kentaro Iwasaki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We prospectively evaluated refractive changes in the eyes of 97 patients who underwent trabeculectomy at Fukui University Hospital, Fukui, Japan. The primary outcome measure was the refractive change after trabeculectomy. Secondary outcome measures included postoperative complications and prognostic factors for refractive change. We observed a progressive and significant mean refractive myopic shift of −0.80 D at 12 months after surgery. In phakic eyes, the mean myopic refractive shifts progressed significantly by −0.46 D at 3 months after surgery (), by −0.52 D at 6 months (), and by −1.31 D at 12 months (). In the pseudophakic eyes, we found no significant refraction progression at any of the postsurgery follow-up visits. Our multivariable analyses showed that lens nuclear color grade change was a significant prognostic factor for refractive myopic progression (). Trabeculectomy causes refractive myopic progression in phakic eyes. Nuclear sclerotic cataract progression is associated with refractive myopic shift after trabeculectomy. This trail is registered with UMIN000007813.