Clinical and Ultrastructural Studies of Gelatinous Drop-Like Corneal Dystrophy (GDLD) of a Patient with TACSTD2 Gene Mutation

Figure 3

Electron micrograph of GDLD cornea. (a) Part of a degenerated epithelium containing degenerated tight junctions and normal tight junctions. Note that most of the tight junctions are degenerated forming electron-lucent spaces. (b) Numerous running randomly amyloid fibrils deposits at subepithelial region; (c, d) a network of amyloid fibrils at high magnification at subepithelial region; (e) part of the anterior stroma showing a degenerated lamellae and electron-lucent spaces; (f) the stromal amyloid fibrils associated with collagen fibrils. AM: amyloid deposits; CF: collagen fibrils; E: epithelium; L: lamella, TD: degenerated tight junctions; NT: normal tight junctions.

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