Clinical Features of Primary and Systemic Metastatic Intraocular Lymphomas in Spanish Patients

Figure 1

(a) Ultra-wide field pseudocolor retinography of the right eye of a 42 year-old black male. Currently in systemic remission, he was diagnosed with peripheral blood diffuse large B-cell lymphoma (DLBCL) 10 months before. Creamy whitish subretinal infiltrates with some hemorrhages suggested secondary metastatic retinal lymphoma (SRML). (b) Swept-source optical coherence tomography showed a sheet of vitreous cells. (c) Retinal biopsy (Hematoxylin-Eosin, 200x) confirmed intraocular diffuse large B-cell lymphoma. Note the large atypical cells admixed with coagulative necrosis. Bar size = 100 μm. (d) The cell showed a diffuse and strong positivity for CD20. Bar size = 100 μm. (e) Vitreous cytology (Diff-quick, 600x), atypical large cells with variable morphology and accompanying lymphocytes. Bar size = 50 μm. (f) Vitreous cytology of the same sample (Diff-quick, 400x) showing multiple lymphocytes and macrophages. Bar size = 50 μm.

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