Corneal Safety and Stability in Cases of Small Incision Lenticule Extraction with Collagen Cross-Linking (SMILE Xtra)
Table 3
Average keratometry readings, central corneal thickness, and endothelial cell count along the postoperative follow-up period.
1 month
3 months
6 months
12 months
24 months
SMILE Xtra: K readings (D)
36.4 ± 1.8
36.3 ± 1.7
36.2 ± 1.6
36.1 ± 1.6
36.1 ± 1.7
SMILE: K readings (D)
36.2 ± 1.6
36.4 ± 1.8
36.3 ± 1.6
36.4 ± 1.7
36.3 ± 1.8
value
0.388
0.585
0.457
0.399
0.416
SMILE Xtra: CCT (microns)
408.1 ± 42.6
402.3 ± 41.6
405.1 ± 42.2
407.3 ± 40.6
407.3 ± 41.6
SMILE: CCT (microns)
412.2 ± 39.8
410.6 ± 40.8
412.5 ± 39.6
411.2 ± 38.8
413.2 ± 39.5
value
0.179
0.265
0.048
0.066
0.041
SMILE Xtra: ECD (cells/mm2)
2776 ± 318
2775 ± 298
2780 ± 295
2776 ± 310
2790 ± 300
SMILE: ECD (cells/mm2)
2815 ± 288
2818 ± 278
2813 ± 286
2819 ± 280
2810 ± 298
value
0.654
0.644
0.599
0.623
0.610
Values are expressed as mean ± SD. D: diopters; K: keratometry; CCT: central corneal thickness; ECD: endothelial cell density; value compares mean of SMILE Xtra vs. SMILE using independent-samples t-test. Statistically significant.
