Research Article
HGF-rs12536657 and Ocular Biometric Parameters in Hyperopic Children, Emmetropic Adolescents, and Young Adults: A Multicenter Quantitative Trait Study
Table 1
Baseline refractive and biometric measurements for cases (hyperopic children) and controls (emmetropic children and emmetropic adults).
| | | Hyperopic children () | Emmetropic children () | Emmetropic adults () |
| | Age (years) | 8.23 (2.62) | 16.48 (1.18) | 22.26 (2.55) | | Gender (female) | 81 (43.1%) | 25 (48.1%) | 103 (63.2%) | | | Mean (SD) | Mean (SD) | Mean (SD) | | | RE | LE | RE | LE | RE | LE | | SE | +5.71 (1.47) | +5.87 (1.46) | +0.07 (0.45) | +0.07 (0.46) | +0.05 (0.45) | +0.05 (0.44) | | Sphere | +6.20 (1.57) | +6.39 (1.53) | +0.14 (0.45) | +0.14 (0.45) | +0.16 (0.47) | +0.19 (0.45) | | Cylinder | −0.98 (0.88) | −1.05 (0.87) | −0.14 (0.24) | −0.15 (0.26) | −0.22 (0.25) | −0.28 (0.25) | | Kflat TOP | 41.99 (1.40) | 42.03 (1.39) | 42.54 (1.46) | 42.62 (1.42) | 43.30 (1.37) | 43.43 (1.30) | | Ksteep TOP | 43.54 (1.41) | 43.61 (1.39) | 43.12 (1.47) | 43.35 (1.46) | 43.93 (1.38) | 44.13 (1.32) | | Kmean TOP | 42.76 (1.33) | 42.82 (1.32) | 42.83 (1.45) | 42.87 (1.46) | 43.61 (1.36) | 43.69 (1.33) | | ACD TOP | 2.88 (0.28) | 2.89 (0.28) | 3.28 (0.31) | 3.26 (0.30) | 3.19 (0.25) | 3.19 (0.25) | | WW TOP | 11.99 (0.39) | 11.97 (0.38) | 12.12 (0.37) | 12.13 (0.36) | 12.10 (0.37) | 12.08 (0.38) | | CCT TOP | 564.39 (30.68) | 564.81 (31.26) | 542.48 (34.64) | 543.02 (34.82) | 542.01 (37.67) | 543.48 (36.42) | | AAA TOP | 40.51 (6.92) | 40.49 (8.00) | 45.87 (6.82) | 44.60 (8.31) | 44.16 (6.16) | 43.50 (6.61) | | AL BIOM | 21.20 (0.83) | 21.11 (0.84) | 23.59 (0.73) | 23.55 (0.72) | 23.40 (0.71) | 23.35 (0.72) | | Kflat BIOM | 42.06 (1.39) | 42.08 (1.41) | 42.61 (1.45) | 42.56 (1.45) | 43.35(1.37) | 43.36 (1.35) | | Ksteep BIOM | 43.69 (1.44) | 43.79 (1.42) | 43.27 (1.44) | 43.19 (1.48) | 44.03(1.35) | 44.01 (1.35) | | Kmean BIOM | 42.88 (1.33) | 42.94 (1.34) | 42.94 (1.44) | 42.99 (1.43) | 43.69(1.34) | 43.78 (1.30) | | ACD BIOM | 3.28 (0.26) | 3.28 (0.27) | 3.61 (0.32) | 3.62 (0.30) | 3.62(0.25) | 3.63 (0.24) | | WW BIOM | 12.19 (0.38) | 12.16 (0.41) | 12.20 (0.31) | 12.23 (0.28) | 12.08(0.56) | 12.15 (0.41) |
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LE: left eye; RE: right eye; BIOM: IOL master measurements; TOP: topography measurements; SE: spherical equivalent (diopters); Kflat: anterior flat keratometry (diopters); Ksteep: anterior steep keratometry (diopters); Kmean: anterior mean keratometry (diopters); AL: axial length (mm); ACD: anterior chamber depth (mm); WW: white-to-white diameter (mm); CCT: central corneal thickness (microns); ACA: anterior chamber angle (degrees).
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