Comparative Study on the Efficacy and Safety of Tumor Resection in Vitrectomy for Retinal Vasoproliferative Tumors

Figure 1

Case 6, female, 42 years old, decreased vision in the left eye with 1 week of shadow flutters before eye, best-corrected visual acuity 0.5, vitreous bloody opacity, cells (++), blurred fundus, and 2PD pink tumor in the inferior temporal area. (a–c) Before the first surgery: (a) color photo of the fundus; (b) fluorescein angiography at 2 minutes and 15 seconds, a mottled hyperfluorescent zone was seen in the inferior temporal location, where the vessels dilated like tumor with obvious surrounding capillary leakage; (c) fluorescein angiography at 2 minutes and 28 seconds, where some blood vessels entered the hyperfluorescence phase with uneven diameters and slightly expanded (flat arrows). (d) FA angiography at 2 minutes and 46 seconds shows a clear boundary between the subretinal effusion and the normal retina, and the common leakage of capillaries. (e) ICG angiography at 1 minute and 16 seconds shows that the blood vessels in the lesion expand and distort, mostly in coarse granules, clustered into clusters, and the plaque-like fluorescence filling in the tumor. (f) ICG angiography at 10 minutes and 14 seconds. At this time, the intensity of intravascular fluorescence decreased and part of the tumor area also reduced, resulting in a high fluorophore mass. She was injected anti-VEGF once and triamcinolone acetonide twice, while her condition could not be controlled. The BCVA before the second surgery was 0.05. (g) Optomap illustrated retinal detachment and hard exudation involving the posterior pole. No conservative treatment was performed after surgery, and BCVA at 30 months after surgery was 0.1. (h) the Opel image showed that the pigment epithelium of the original detached area was atrophic, scarring, and affected by the macular center.