Clinical Study

One-Year Outcomes of 1 Dose versus 3 Loading Doses Followed by Pro Re Nata Regimen Using Ranibizumab for Neovascular Age-Related Macular Degeneration: The ARTIS Trial

Table 1

Baseline characteristics of the patients in two groups.

1 + PRN3 + PRNP value

Patients (no.)4549
Age (mean ± SD)69.7 ± 8.670.0 ± 8.80.855
Male/female30/1530/190.583
Right/left eye (no.)28/1725/240.274
Letters of BCVA (mean ± SD)49.0 ± 16.252.0 ± 13.90.341
<30 letters (no.)830.079
30–60 letters (no.)27330.459
>60 letters (no.)10130.629
CRT (μm, mean ± SD)468 ± 202428 ± 1630.290
Eyes with PCV (%)4 (8.9%)4 (8.2%)0.900
Pseudophakic240.461
Patients with hypertension10120.795
Patients with diabetes130.439
Hyperthyroidism100.479

BCVA, best-corrected visual acuity; CRT, central retinal thickness; PCV, polypoidal choroidal vasculopathy; PRN, pro re nata; SD, standard deviation.