One-Year Outcomes of 1 Dose versus 3 Loading Doses Followed by Pro Re Nata Regimen Using Ranibizumab for Neovascular Age-Related Macular Degeneration: The ARTIS Trial
Table 1
Baseline characteristics of the patients in two groups.
1 + PRN
3 + PRN
P value
Patients (no.)
45
49
Age (mean ± SD)
69.7 ± 8.6
70.0 ± 8.8
0.855
Male/female
30/15
30/19
0.583
Right/left eye (no.)
28/17
25/24
0.274
Letters of BCVA (mean ± SD)
49.0 ± 16.2
52.0 ± 13.9
0.341
<30 letters (no.)
8
3
0.079
30–60 letters (no.)
27
33
0.459
>60 letters (no.)
10
13
0.629
CRT (μm, mean ± SD)
468 ± 202
428 ± 163
0.290
Eyes with PCV (%)
4 (8.9%)
4 (8.2%)
0.900
Pseudophakic
2
4
0.461
Patients with hypertension
10
12
0.795
Patients with diabetes
1
3
0.439
Hyperthyroidism
1
0
0.479
BCVA, best-corrected visual acuity; CRT, central retinal thickness; PCV, polypoidal choroidal vasculopathy; PRN, pro re nata; SD, standard deviation.