Research Article
Increased Plasma Levels of 8-Hydroxy-2′-deoxyguanosine (8-OHdG) in Patients with Pseudoexfoliation Glaucoma
Table 1
Demographic characteristics and 8-hydroxydeoxyguanosine (8-OHdG) levels between pseudoexfoliation glaucoma cases and controls.
| Variables | Cases () | Controls () | value |
| Age in years, mean (SD) | 62.27 (6.31) | 59.91 (8.33) | 0.146a | Male/female, n | 26/15 | 30/15 | 0.751b | Systemic diseases, n (%) | | | | Diabetes mellitus | 6 (14.6) | 6 (13.3) | 0.862b | Hypertension | 4 (9.7) | 5 (11.1) | 0.605b | Coronary artery disease | 2 (4.8) | 2 (4.4) | 0.924b | Hypercholesterolemia | 3 (7.3) | 2 (4.4) | 0.569b | Family history of glaucoma | 5 (12.2) | 1 (2.2) | 0.069b | Smokers | 5 (12.2) | 5 (11.1) | 0.874b |
| 8-OHdG concentration, ng/mL | | | | Mean (SD) | 30.48 (31.52) | 16.95 (10.66) | 0.008a | Median | 18.11 | 13.78 | 0.032c |
| By gender | | | | Males, mean (SD) | 29.53 (26.94) | 17.02 (11.02) | 0.023a | Median | 18.17 | 13.12 | 0.041c | Females, mean (SD) | 32.12 (39.22) | 16.80 (10.29) | 0.154a | Median | 17.68 | 17.97 | 0.442c |
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Notes. aIndependent sample t-test (two-tailed); bchi-square test; cMann–Whitney U test.
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