Research Article

Increased Plasma Levels of 8-Hydroxy-2′-deoxyguanosine (8-OHdG) in Patients with Pseudoexfoliation Glaucoma

Table 3

Levels of 8-hydroxydeoxyguanosine (8-OHdG) according to LOXL1 rs1048661 and rs3835942 polymorphisms in pseudoexfoliation glaucoma cases and controls.

LOXL1 genotypes8-OHdG ng/mL, mean (SD) value
ControlsCases

rs1048661
G/G18.55 (12.04)30.16 (17.90)0.236
G/T13.71 (8.16)21.99 (19.31)0.617
T/T7.84
G/T + T/T13.26 (7.98)21.99 (19.31)0.469

rs3825942
G/G18.53 (10.68)28.89 (30.97)0.369
G/A12.93 (11.46)11.83
A/A16.13 (11.33)
G/A + A/A14.00 (11.11)11.83

Note. values tested within groups using G/G as reference by the Mann–Whitney U test were also nonsignificant ().