Multiple Gene Polymorphisms Associated with Exfoliation Syndrome in the Uygur Population

Table 6

Haplotype association analysis between these SNPs.

Gene	Haplotype		Case (proportion)	Control (proportion)	value	OR	95% CI
	rs41435250	rs893818
LOXL1	G	A	83 (0.165)	210 (0.322)	≤0.001	0.417	0.313–0.556
	T	G	122 (0.243)	100 (0.153)	≤0.001	1.772	1.320–2.380
	G	G	296 (0.590)	342 (0.525)	0.028	1.302	1.030–1.648
	rs429358	rs7412
APOE	T	C	418 (0.833)	545 (0.836)	0.884	0.977	0.715–1.336
	C	C	50 (0.100)	65 (0.100)	0.996	0.999	0.677–1.473
	C	T	34 (0.068)	42 (0.064)	0.822	1.055	0.661–1.685
	rs2107856	rs2141388
CNTNAP2	T	T	201 (0.400)	261 (0.400)	0.998	1.000	0.789–1.269
	G	C	299 (0.596)	390 (0.598)	0.930	0.990	0.781–1.254

The haplotypes GG/TG/GA for the SNPs rs41435250 and rs893818 were significantly associated with XFS/XFG.