Research Article
Multiple Gene Polymorphisms Associated with Exfoliation Syndrome in the Uygur Population
Table 7
Haplotype (adjusted) association analysis between these SNPs.
| | Gene | Haplotype | Case (proportion) | Control (proportion) | value | OR | 95% CI |
| | | rs41435250 | rs893818 | | | | | | | LOXL1 | G | A | 67 (0.155) | 189 (0.319) | ≤0.001 | 0.400 | 0.286–0.559 | | T | G | 101 (0.234) | 89 (0.150) | 0.001 | 1.769 | 1.251–2.503 | | G | G | 264 (0.611) | 314 (0.530) | 0.029 | 1.356 | 1.032–1.782 |
| | | rs429358 | rs7412 | | | | | | | APOE | T | C | 360 (0.833) | 494 (0.834) | 0.609 | 0.910 | 0.634–1.307 | | C | C | 42 (0.097) | 57 (0.096) | 0.643 | 1.113 | 0.707–1.753 | | C | T | 30 (0.069) | 41 (0.069) | 0.834 | 1.059 | 0.621–1.806 |
| | | rs2107856 | rs2141388 | | | | | | | CNTNAP2 | T | T | 180 (0.417) | 239 (0.404) | 0.569 | 1.083 | 0.823–1.424 | | G | C | 250 (0.579) | 352 (0.595) | 0.523 | 0.915 | 0.696–1.202 |
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The haplotypes GG/TG/GA for the SNPs rs41435250 and rs893818 were significantly associated with XFS/XFG.
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