Twenty-Four-Hour Contact Lens Sensor Monitoring of Aqueous Humor Dynamics in Surgically or Medically Treated Glaucoma Patients

Table 1

Demographics and clinical data of subjects.

	Ex-PRESS (Group 1)	Hydrus (Group 2)	Drug therapy (Group 3)	Group 1 vs. Group 2 (p value)	Group 1 vs. Group 3 (p value)	Group 2 vs. Group 3 (p value)
Age (years)	71.12 ± 11.42	77.75 ± 4.62	73.25 ± 4.78	0.14	0.88	0.07
Sex (M/F)	17/12 (29)	11/17 (28)	11/21 (32)	—	—	—
Eye laterality (right/left)	17/12 (29)	9/19 (28)	13/19 (32)	—	—	—
GAT-IOP before CLS application (mmHg)	17.62 ± 3.42	16.62 ± 3.11	17.25 ± 3.11	0.59	0.89	0.59
GAT-IOP after CLS removal (mmHg)	14.25 ± 2.55	15.65 ± 1.60	15.87 ± 3.90	0.23	0.45	0.78
CCT (µm)	474 ± 47.27	515.12 ± 20.25	528.12 ± 18.43	0.082	0.016	0.15
MD of SAP (dB)	−14.37 ± 9.74	−5.00 ± 2.22	−6.07 ± 2.19	0.021	0.038	0.38
PSD of SAP (dB)	9.42 ± 4.61	4.21 ± 2.13	6.38 ± 3.05	0.015	0.16	0.13

Data are expressed as mean ± SD, except for sex and eye laterality. SD, standard deviation; p, probability value of statistical hypothesis testing; GAT-IOP, Goldmann applanation tonometry intraocular pressure; CLS, contact lens sensor; CCT, central corneal thickness; MD, mean deviation; SAP, standard automated perimetry; PSD, pattern standard deviation; mmHg, millimeters of mercury; dB, decibel. Significant values by the Mann–Whitney U-test with Bonferroni’s correction for multiple comparisons ().