Twenty-Four-Hour Contact Lens Sensor Monitoring of Aqueous Humor Dynamics in Surgically or Medically Treated Glaucoma Patients
Table 2
Circadian indicators.
Ex-PRESS (Group 1)
Hydrus (Group 2)
Drug therapy (Group 3)
Group 1 vs. Group 2 (p value)
Group 1 vs. Group 3 (p value)
Group 2 vs. Group 3 (p value)
Observed circadian pattern, n/n (%)
29/29 (100)
28/28 (100)
32/32 (100)
—
—
—
Nocturnal pattern recorded, n/n (%)
29/29 (100)
28/28 (100)
32/32 (100)
—
—
—
Coefficient ω
0.021 ± 0.00
0.025 ± 0.01
0.021 ± 0.00
0.26
0.62
0.13
Fluctuation range (mVEq)
319.32 ± 53.26
305.75 ± 9.44
477.70 ± 92.74
0.57
0.003
0.010
Maximum (mVEq)
221.22 ± 60.04
149.39 ± 97.49
267.97 ± 85.38
0.08
0.33
0.021
Minimum (mVEq)
−98.11 ± 58.86
−156.36 ± 91.63
−209.72 ± 97.53
0.06
0.015
0.033
Acrophase (h)
04 : 53 ± 1 : 59
04 : 01 ± 2 : 51
22 : 26 ± 4 : 58
0.98
0.009
0.083
Bathyphase (h)
14 : 19 ± 2 : 22
14 : 11 ± 3 : 23
11 : 12 ± 1 : 18
0.57
0.002
0.041
Data are expressed as mean ± SD, except for observed circadian pattern and eye nocturnal pattern recorded. SD, standard deviation; p, probability value of statistical hypothesis testing; n, number of patients; mVEq, millivolt equivalent, an arbitrary unit provided by the contact lens sensor; h, hours. Significant values by the Mann–Whitney U-test with Bonferroni’s correction for multiple comparisons ().
