Journal of Ophthalmology / 2019 / Article / Tab 2

Research Article

Twenty-Four-Hour Contact Lens Sensor Monitoring of Aqueous Humor Dynamics in Surgically or Medically Treated Glaucoma Patients

Table 2

Circadian indicators.

Ex-PRESS (Group 1)Hydrus (Group 2)Drug therapy (Group 3)Group 1 vs. Group 2 (p value)Group 1 vs. Group 3 (p value)Group 2 vs. Group 3 (p value)

Observed circadian pattern, n/n (%)29/29 (100)28/28 (100)32/32 (100)
Nocturnal pattern recorded, n/n (%)29/29 (100)28/28 (100)32/32 (100)
Coefficient ω0.021 ± 0.000.025 ± 0.010.021 ± 0.000.260.620.13
Fluctuation range (mVEq)319.32 ± 53.26305.75 ± 9.44477.70 ± 92.740.570.0030.010
Maximum (mVEq)221.22 ± 60.04149.39 ± 97.49267.97 ± 85.380.080.330.021
Minimum (mVEq)−98.11 ± 58.86−156.36 ± 91.63−209.72 ± 97.530.060.0150.033
Acrophase (h)04 : 53 ± 1 : 5904 : 01 ± 2 : 5122 : 26 ± 4 : 580.980.0090.083
Bathyphase (h)14 : 19 ± 2 : 2214 : 11 ± 3 : 2311 : 12 ± 1 : 180.570.0020.041

Data are expressed as mean ± SD, except for observed circadian pattern and eye nocturnal pattern recorded. SD, standard deviation; p, probability value of statistical hypothesis testing; n, number of patients; mVEq, millivolt equivalent, an arbitrary unit provided by the contact lens sensor; h, hours. Significant values by the Mann–Whitney U-test with Bonferroni’s correction for multiple comparisons ().