Secondary Vitrectomy with Internal Limiting Membrane Plug due to Persistent Full-Thickness Macular Hole OCT-Angiography and Microperimetry Features: Case Series

Table 1

The results of time period before primary PPV, visual acuity (BCVA) in both eyes, diameter of the hole in OCT before and after primary vitrectomy in eyes operated twice (EOT), microperimetry parameters (average threshold (AT) and fixation pattern) and OCT-A parameters (foveal avascular zone (FAZ), and foveal vessel density (FVDS) in EOT with pars plana vitrectomy (PPV) due to persistent full-thickness macular hole (FTMH) and fellow eyes (FE).

	Time period from diagnosis to surgery (months)	BCVA		Diameter of the hole (µm)		AT (dB)		Fixation pattern		SD-OCT	FAZ (mm^2)		FVDS (%)
		EOT	FE	Before first PPV	After first PPV	EOT	FE	EOT	FE	EOT	EOT	FE	EOT	FE
Case 1	8	0.3	0.9 healthy	475	452	24.9	27.0	Stable	Stable	V-shape	0.324	0.180	18.3	28.8
Case 2	8	0.1	0.8 operated once	485	765	17.7	27.9	Unstable, eccentric fixation	Unstable	V-shape	0.316	0.158	21.9	33.6
Case 3	7	0.05	0.1 operated once	760	940	12.7	21.7	Unstable, eccentric fixation	Unstable	V-shape, atrophy	0.461	0.416	7.5	18.5
Case 4	6	0.2	0.9 healthy	588	726	20.0	27.9	Unstable	Stable	V-shape	0.537	0.374	9.8	14.6